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Trex2tm1.2Coso
Targeted Allele Detail
Nomenclature
Symbol: Trex2tm1.2Coso
Name: three prime repair exonuclease 2; targeted mutation 1.2, Concepcio Soler
MGI ID: MGI:4355746
Gene: Trex2  Location: ChrX:73433705-73435344 bp, - strand  Genetic Position: ChrX, 37.31 cM, cytoband A6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151766
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exon 2. The absence of protein expression was confirmed by western blot analysis on skin extracts. (J:151766)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trex2 Mutation:  0 strains or lines available
References
Original:  J:151766 Parra D, et al., Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice. Cancer Res. 2009 Aug 15;69(16):6676-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory