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Targeted Allele Detail
Symbol: Ets2tm5.1Rgo
Name: E26 avian leukemia oncogene 2, 3' domain; targeted mutation 5.1, Robert G Oshima
MGI ID: MGI:4353393
Synonyms: Ets2fl, Ets2LoxP
Gene: Ets2  Location: Chr16:95503274-95522093 bp, + strand  Genetic Position: Chr16, 56.64 cM, cytoband C3-qter
Germline Transmission:  Earliest citation of germline transmission: J:151187
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed pgk-neo and HSV-TK cassette was inserted into intron 2 and a single loxP site was inserted into intron 5 via homologous recombination. Cre mediated recombination then removed the selection cassette leaving exons 3, 4 and 5 floxed. (J:151187)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ets2 Mutation:  28 strains or lines available
Original:  J:151187 Wei G, et al., Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009 Jul 30;114(5):1123-30
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.20
The Jackson Laboratory