Ipo11^{Gt(RRU483)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Ipo11^{Gt(RRU483)Byg}
• Name: importin 11; gene trap RRU483, BayGenomics
• MGI ID: MGI:4340740
• Synonyms: Ipo11^hy
• Gene: Ipo11 Location: Chr13:106930947-107073466 bp, - strand Genetic Position: Chr13, 58.06 cM
• Alliance: Ipo11^{Gt(RRU483)Byg} page

Mutation origin

• Mutant Cell Line: RRU483
• Germline Transmission: Earliest citation of germline transmission: J:248576
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. The molecular lesion is an insertion of a gene-trap vector in intron 5. The resulting hypomorphic allele reduced mRNA to <25% of normal levels. (J:248576)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRU483	CL315431 ; (MGI Seq Detail)	5' RACE	Chr13:107046707-107073315 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  115 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ipo11 Mutation: 167 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)