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ShprhGt(RRJ453)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: ShprhGt(RRJ453)Byg
Name: SNF2 histone linker PHD RING helicase; gene trap RRJ453, BayGenomics
MGI ID: MGI:4129965
Synonyms: DELTAShprh
Gene: Shprh  Location: Chr10:11149427-11217595 bp, + strand  Genetic Position: Chr10, 3.66 cM
Mutation
origin
Mutant Cell Line:  RRJ453
Germline Transmission:  Unknown
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsTrapped gene association determined by genome coordinate overlap and strand. The gene trap contains a lacZ reporter gene cassette and neomycin resistance gene cassette. It inserted into intron 16, preventing the transcription of the exons coding for the RING and helicase domains. Western blot and RT-PCR experiments confirm the absence of transcription from exons 17 onward.
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shprh Mutation:  4 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory