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EpcamGt(RST412)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: EpcamGt(RST412)Byg
Name: epithelial cell adhesion molecule; gene trap RST412, BayGenomics
MGI ID: MGI:4127340
Gene: Epcam  Location: Chr17:87635979-87651127 bp, + strand  Genetic Position: Chr17, 57.87 cM
Tufting enteropathy in EpcamGt(RST412)Byg/EpcamGt(RST412)Byg mice

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Mutant Cell Line:  RST412
Germline Transmission:  Earliest citation of germline transmission: J:195002
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1TMpfs     Vector Type: secretory trap
 
Mutation detailsThe gene trap cassette inserted into intron 3. Expression of the fusion transcript is seen in the intestines of heterozygous mice. (J:195002)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Scheme for the generation of the EpcamGt(RST412)Byg and EpcamGt(RST413)Byg alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epcam Mutation:  23 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory