Bcor^Gt(XE541)Byg
Gene trapped Allele Detail

Summary

• Symbol: Bcor^Gt(XE541)Byg
• Name: BCL6 interacting corepressor; gene trap XE541, BayGenomics
• MGI ID: MGI:4126230
• Gene: Bcor Location: ChrX:11902979-12026594 bp, - strand Genetic Position: ChrX, 6.83 cM, cytoband A1.2
• Alliance: Bcor^Gt(XE541)Byg page

Bcor^Gt(XE541)Byg/Y chimera at E9.5 exhibits microcephaly, forebrain fusion, incomplete somite formation and arrested heart development

Show the 9 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: XE541
• Mouse Generated: Earliest citation of chimera generation: J:160967
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• The gene trap vector inserted between exon 5 and 6. (J:163340)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XE541	CC183433 ; (MGI Seq Detail)	5' RACE	ChrX:11921207-11922857 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  23 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcor Mutation: 21 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)