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TardbpGt(RRB030)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: TardbpGt(RRB030)Byg
Name: TAR DNA binding protein; gene trap RRB030, BayGenomics
MGI ID: MGI:4126090
Gene: Tardbp  Location: Chr4:148612382-148627019 bp, - strand  Genetic Position: Chr4, 78.77 cM
Mutation
origin
Mutant Cell Line:  RRB030
Germline Transmission:  Earliest citation of germline transmission: J:158641
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsTrapped gene association determined by genome coordinate overlap and strand. The genetrap vector pGT1LXF was inserted in intron 2 at base pair 1226. The resulting gene product includes only the first 65 amino acids of the native protein fused with betaGeo. All functional domains of the native protein are lost. (J:158641, J:159888)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 98 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tardbp Mutation:  32 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory