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Rnf7Gt(XE423)Byg
Gene trapped Allele Detail
Summary
Symbol: Rnf7Gt(XE423)Byg
Name: ring finger protein 7; gene trap XE423, BayGenomics
MGI ID: MGI:4125996
Synonyms: Saggt
Gene: Rnf7  Location: Chr9:96352990-96360728 bp, - strand  Genetic Position: Chr9, 50.63 cM, cytoband D2.3
Alliance: Rnf7Gt(XE423)Byg page
Mutation
origin
Mutant Cell Line:  XE423
Germline Transmission:  Earliest citation of germline transmission: J:164457
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsThe gene trap vector inserted in the second intron disrupting the transcript and producing a truncated fusion protein that lacks the RING domain. Immunoblot analysis confirmed the absence of protein expression in homozygous embryos. (J:178926)
Sequence Tags: 
Sequence tag details (1 tag)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rnf7 Mutation:  17 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory