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CicGt(XE565)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: CicGt(XE565)Byg
Name: capicua transcriptional repressor; gene trap XE565, BayGenomics
MGI ID: MGI:4125985
Synonyms: Cic-L-
Gene: Cic  Location: Chr7:25267704-25294159 bp, + strand  Genetic Position: Chr7, 13.73 cM
Mutation
origin
Mutant Cell Line:  XE565
Germline Transmission:  Earliest citation of germline transmission: J:177841
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
 
Mutation detailsThe gene trap vector inserted downstream of exon 1. The absence of protein expression of the long isoform was confirmed by western blot anaylsis. The expression of the short isoform is reduced to 10% of wild-type. (J:177841)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cic Mutation:  68 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory