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Ash1lGt(AL0395)Wtsi
Gene trapped Allele Detail
Nomenclature
Symbol: Ash1lGt(AL0395)Wtsi
Name: ASH1 like histone lysine methyltransferase; gene trap AL0395, Wellcome Trust Sanger Institute
MGI ID: MGI:3852878
Synonyms: Ash1lGT
Gene: Ash1l  Location: Chr3:88857929-88986682 bp, + strand  Genetic Position: Chr3, 39.01 cM
Mutation
origin
Mutant Cell Line:  AL0395
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Hypomorph)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsA gene trap vector, pGT01xf, containing the beta-geo reporter gene (beta-galactosidase and neomycin resistance fusion gene) was inserted into intron 1 of the Ash1l gene. Immunohistochemical analysis of uterus tissue from 3 and 4 week old homozygous females and epididymis from homozygous males also shows diminished Ash1l protein. (J:101977)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ash1l Mutation:  81 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory