About   Help   FAQ
Tg(Myh6/NFAT-luc)1Jmol
Transgene Detail
Nomenclature
Symbol: Tg(Myh6/NFAT-luc)1Jmol
Name: transgene insertion 1, Jeffery D Molkentin
MGI ID: MGI:3851596
Synonyms: NFAT-luc, Tg(NFAT luc reporter)
Transgene: Tg(Myh6/NFAT-luc)1Jmol  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsNine copies of a nuclear factor of activated T cell (NFAT) binding site (5'-TGGAAAATT-3') from the interleukin 4 (Il4) promoter were placed 5' to a mouse alpha myosin heavy chain (Myh6) and upstream of a luciferase promoter. (J:83547)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:83547 Braz JC, et al., Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. J Clin Invest. 2003 May;111(10):1475-86
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory