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Tg(tetO-Dusp6)1Jmol
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Dusp6)1Jmol
Name: transgene insertion 1, Jeffery D Molkentin
MGI ID: MGI:3851561
Synonyms: Tg(DUSP6)
Transgene: Tg(tetO-Dusp6)1Jmol  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-Dusp6)1Jmol expresses 1 gene
 
Mutation detailsA tetracycline-responsive element (TRE; tetO) and mouse alpha myosin heavy chain minimal promoter regulate expression of Myc-tagged mouse Dusp6. The transgenic line was created and maintained on an FVB background. Copy number was not determined. (J:124903)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:124903 Purcell NH, et al., Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14074-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory