About   Help   FAQ
Tg(Kera-PITX2*A)BHjal
Transgene Detail
Nomenclature
Symbol: Tg(Kera-PITX2*A)BHjal
Name: transgene insertion B, Tord Hjalt
MGI ID: MGI:3851245
Synonyms: Ktcn-PITX2
Transgene: Tg(Kera-PITX2*A)BHjal  Location: unknown  
Transgene
origin
Strain of Origin:  (CBA x C57BL/6)F2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Kera-PITX2*A)BHjal expresses 1 gene
 
Mutation detailsA transgenic construct containing cDNA for the human paired-like homeodomain 2, human, PITX2A, isoform under the control of the mouse keratocan ( Kera) promoter, and rabbit beta-globin polyA signal sequences was injected into fertilized CBAB6F2 mouse eggs. Numerous founders were obtained. In line B, multiple copies were found to be integrated on chromosome 12B3. Lines A and B display identical phenotypes. (J:93634)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:93634 Holmberg J, et al., PITX2 gain-of-function in rieger syndrome eye model. Am J Pathol. 2004 Nov;165(5):1633-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory