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Tg(GFAP-CRYAB)141.6Mes
Transgene Detail
Nomenclature
Symbol: Tg(GFAP-CRYAB)141.6Mes
Name: transgene insertion 141.6, Albee Messing
MGI ID: MGI:3850461
Synonyms: CryabTg, CryabTg
Transgene: Tg(GFAP-CRYAB)141.6Mes  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(GFAP-CRYAB)141.6Mes expresses 1 gene
 
Mutation detailsA transgenic construct containing the hamster Cryab, alpha B crystalline gene under the control of the human GFAP, glial fibrillary acidic protein, promoter was injected into fertilized FVB/N mouse eggs. Founder line 141.6 was subsequently established. (J:146191)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:146191 Hagemann TL, et al., Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease. Hum Mol Genet. 2009 Apr 1;18(7):1190-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory