Rictortm1.1Mnh
Targeted Allele Detail
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Symbol: |
Rictortm1.1Mnh |
Name: |
RPTOR independent companion of MTOR, complex 2; targeted mutation 1.1, Michael N Hall |
MGI ID: |
MGI:3850086 |
Synonyms: |
rictorfl |
Gene: |
Rictor Location: Chr15:6737860-6829882 bp, + strand Genetic Position: Chr15, 3.25 cM, cytoband A1
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Alliance: |
Rictortm1.1Mnh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:150064
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A Frt-flanked neomycin cassette and a loxP site were inserted upstream of exon 4 with an additional loxP site inserted downstream of exon 5. Founder mice were crossed with Flpe transgenic mice to remove the neo cassette leaving exons 4-5 floxed. Gene expression was unaffected as determined by immunoblot analysis of adipose tissue.
(J:150064)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rictor Mutation: |
140 strains or lines available
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Original: |
J:150064 Cybulski N, et al., mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9902-7 |
All: |
14 reference(s) |
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