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Glis3tm1Hiha
Targeted Allele Detail
Nomenclature
Symbol: Glis3tm1Hiha
Name: GLIS family zinc finger 3; targeted mutation 1, Hisashi Hashimoto
MGI ID: MGI:3849863
Gene: Glis3  Location: Chr19:28258851-28680077 bp, - strand  Genetic Position: Chr19, 22.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150077
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5, which contains most of the zinc finger motifs, was replaced with a floxed pgk-neo cassette via homologous recombination. (J:150077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Glis3 Mutation:  26 strains or lines available
References
Original:  J:150077 Watanabe N, et al., A murine model of neonatal diabetes mellitus in Glis3-deficient mice. FEBS Lett. 2009 Jun 18;583(12):2108-13
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/16/2018
MGI 6.12
The Jackson Laboratory