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Gcnt4tm1.1Jxm
Targeted Allele Detail
Nomenclature
Symbol: Gcnt4tm1.1Jxm
Name: glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase); targeted mutation 1.1, Jamey Marth
MGI ID: MGI:3849682
Synonyms: C2GnT3-, Gcnt4-
Gene: Gcnt4  Location: Chr13:96924689-96950906 bp, + strand  Genetic Position: Chr13, 50.66 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149909
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMice containing the floxed Gm73tm1Jxm allele were crossed with cre transgenic mice to create a null allele by excision of the single coding exon. Excision of the exon was confirmed by Southern blotting of homozygote tissue extracts. (J:149909)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcnt4 Mutation:  2 strains or lines available
References
Original:  J:149909 Stone EL, et al., Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol. 2009 Jul;29(13):3770-82
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory