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Klf5tm1Yfk
Targeted Allele Detail
Nomenclature
Symbol: Klf5tm1Yfk
Name: Kruppel-like factor 5; targeted mutation 1, Yoshiaki Fujii-Kuriyama
MGI ID: MGI:3849301
Synonyms: Bteb2-
Gene: Klf5  Location: Chr14:99298691-99313412 bp, + strand  Genetic Position: Chr14, 49.43 cM, cytoband E2.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149868
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a lacz-neomycin cassette. Correct targeting was confirmed by Southern blotting. (J:149868)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klf5 Mutation:  11 strains or lines available
References
Original:  J:149868 Ema M, et al., Kruppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell. 2008 Nov 6;3(5):555-67
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory