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Tpcn2Gt(YHD437)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: Tpcn2Gt(YHD437)Byg
Name: two pore segment channel 2; gene trap YHD437, BayGenomics
MGI ID: MGI:3848998
Synonyms: Tpcn2YHD437
Gene: Tpcn2  Location: Chr7:145186524-145284011 bp, - strand  Genetic Position: Chr7, 89.02 cM
Mutation
origin
Mutant Cell Line:  YHD437 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:149472
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
    The gene trap vector pGTOLxf, which contains a beta-geo cassette, inserted between exon 1 and 2. (J:149472)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tpcn2 Mutation:  27 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:149472 Calcraft PJ, et al., NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 2009 May 28;459(7246):596-600
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory