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Gene trapped Allele Detail
Symbol: Tpcn2Gt(YHD437)Byg
Name: two pore segment channel 2; gene trap YHD437, BayGenomics
MGI ID: MGI:3848998
Synonyms: Tpcn2YHD437
Gene: Tpcn2  Location: Chr7:145186524-145284011 bp, - strand  Genetic Position: Chr7, 89.02 cM
Mutant Cell Line:  YHD437 (BayGenomics)
Germline Transmission:  Earliest citation of germline transmission: J:149472
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
    The gene trap vector pGTOLxf, which contains a beta-geo cassette, inserted between exon 1 and 2. (J:149472)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tpcn2 Mutation:  27 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:149472 Calcraft PJ, et al., NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 2009 May 28;459(7246):596-600
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory