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Cdkn2atm1Sxs
Targeted Allele Detail
Nomenclature
Symbol: Cdkn2atm1Sxs
Name: cyclin-dependent kinase inhibitor 2A; targeted mutation 1, Stephen X Skapek
MGI ID: MGI:3848992
Synonyms: ArflacZ
Gene: Cdkn2a  Location: Chr4:89274471-89294653 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149526
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon1b was replaced with a cassette containing lacZ and neo in opposite orientations. LacZ expression recapitulates endogenous gene expression in the eye and testis. (J:149526)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2a Mutation:  23 strains or lines available
References
Original:  J:149526 Freeman-Anderson NE, et al., Expression of the Arf tumor suppressor gene is controlled by Tgf{beta}2 during development. Development. 2009 Jun;136(12):2081-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory