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Zfxtm1.1Reiz
Targeted Allele Detail
Nomenclature
Symbol: Zfxtm1.1Reiz
Name: zinc finger protein X-linked; targeted mutation 1.1, Boris Reizis
MGI ID: MGI:3848796
Synonyms: Zfxflox
Gene: Zfx  Location: ChrX:94074631-94123702 bp, - strand  Genetic Position: ChrX, 41.48 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149654
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 10 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 11. Transient flp expression removed the neo cassette leaving exons 10 and 11 floxed. (J:149654)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfx Mutation:  25 strains or lines available
References
Original:  J:149654 Galan-Caridad JM, et al., Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell. 2007 Apr 20;129(2):345-57
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory