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Mogat2tm1Far
Targeted Allele Detail
Nomenclature
Symbol: Mogat2tm1Far
Name: monoacylglycerol O-acyltransferase 2; targeted mutation 1, Bob Farese
MGI ID: MGI:3848538
Gene: Mogat2  Location: Chr7:99219084-99238619 bp, - strand  Genetic Position: Chr7, 54.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149373
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on intestinal extracts. (J:149373)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mogat2 Mutation:  10 strains or lines available
References
Original:  J:149373 Yen CL, et al., Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nat Med. 2009 Apr;15(4):442-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory