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Nxf2tm1.2Jw
Targeted Allele Detail
Nomenclature
Symbol: Nxf2tm1.2Jw
Name: nuclear RNA export factor 2; targeted mutation 1.2, Jeremy Wang
MGI ID: MGI:3848439
Gene: Nxf2  Location: ChrX:134944526-134964754 bp, - strand  Genetic Position: ChrX, 56.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149228
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exons 3 through 11. The absence of protein expression was confirmed by western blot analysis of testes extracts. (J:149228)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nxf2 Mutation:  2 strains or lines available
References
Original:  J:149228 Pan J, et al., Inactivation of Nxf2 causes defects in male meiosis and age-dependent depletion of spermatogonia. Dev Biol. 2009 Jun 1;330(1):167-74
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory