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Hsf4tm1Xyk
Targeted Allele Detail
Nomenclature
Symbol: Hsf4tm1Xyk
Name: heat shock transcription factor 4; targeted mutation 1, Xiangyin Kong
MGI ID: MGI:3848361
Gene: Hsf4  Location: Chr8:105269801-105275845 bp, + strand  Genetic Position: Chr8, 53.04 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149354
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 3-5 were replaced with a PGK-neomycin resistance cassette. (J:149354)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hsf4 Mutation:  12 strains or lines available
References
Original:  J:149354 Shi X, et al., Removal of Hsf4 leads to cataract development in mice through down-regulation of gamma S-crystallin and Bfsp expression. BMC Mol Biol. 2009;10:10
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory