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Targeted Allele Detail
Symbol: Nr0b2tm1.1Mjev
Name: nuclear receptor subfamily 0, group B, member 2; targeted mutation 1.1, Mark J Evans
MGI ID: MGI:3847927
Synonyms: SHP-
Gene: Nr0b2  Location: Chr4:133553376-133556536 bp, + strand  Genetic Position: Chr4, 66.25 cM
Germline Transmission:  Earliest citation of germline transmission: J:149005
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsGerm line, cre mediated recombination removed exon 1. The absence of transcript expression was confirmed by real-time PCR on liver and ileum extracts. (J:149005)
Generation of Nr0b2tm1Mjev and Nr0b2tm1.1Mjev alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr0b2 Mutation:  9 strains or lines available
Original:  J:149005 Hartman HB, et al., Loss of small heterodimer partner expression in the liver protects against dyslipidemia. J Lipid Res. 2009 Feb;50(2):193-203
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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