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Nr0b2tm1.1Mjev
Targeted Allele Detail
Nomenclature
Symbol: Nr0b2tm1.1Mjev
Name: nuclear receptor subfamily 0, group B, member 2; targeted mutation 1.1, Mark J Evans
MGI ID: MGI:3847927
Synonyms: SHP-
Gene: Nr0b2  Location: Chr4:133553376-133556536 bp, + strand  Genetic Position: Chr4, 66.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149005
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exon 1. The absence of transcript expression was confirmed by real-time PCR on liver and ileum extracts. (J:149005)
Generation of Nr0b2tm1Mjev and Nr0b2tm1.1Mjev alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr0b2 Mutation:  7 strains or lines available
References
Original:  J:149005 Hartman HB, et al., Loss of small heterodimer partner expression in the liver protects against dyslipidemia. J Lipid Res. 2009 Feb;50(2):193-203
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory