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Tsc22d1tm1Clgr
Targeted Allele Detail
Summary
Symbol: Tsc22d1tm1Clgr
Name: TSC22 domain family, member 1; targeted mutation 1, Michael Caligiuri
MGI ID: MGI:3847243
Synonyms: TSC-22-
Gene: Tsc22d1  Location: Chr14:76652401-76745205 bp, + strand  Genetic Position: Chr14, 40.44 cM
Alliance: Tsc22d1tm1Clgr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148897
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on bone marrow cells. (J:148897)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tsc22d1 Mutation:  89 strains or lines available
References
Original:  J:148897 Yu J, et al., TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia. Blood. 2009 May 28;113(22):5558-67
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory