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Vash1tm1Ysat
Targeted Allele Detail
Nomenclature
Symbol: Vash1tm1Ysat
Name: vasohibin 1; targeted mutation 1, Yasufumi Sato
MGI ID: MGI:3846783
Gene: Vash1  Location: Chr12:86678700-86692091 bp, + strand  Genetic Position: Chr12, 40.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148726
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA loxP/FRT flanked neomycin selection cassette replaced 6.6 kb of the locus, including exon 1 that contains the ATG start codon. Gene inactivation was confirmed by a lack of signal in RT-PCR analysis of ear skin. (J:148726)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vash1 Mutation:  7 strains or lines available
References
Original:  J:148726 Kimura H, et al., Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis. Blood. 2009 May 7;113(19):4810-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory