About   Help   FAQ
Nelfbtm1.1Roli
Targeted Allele Detail
Summary
Symbol: Nelfbtm1.1Roli
Name: negative elongation factor complex member B; targeted mutation 1.1, Rong Li
MGI ID: MGI:3846130
Synonyms: Cobra1fl
Gene: Nelfb  Location: Chr2:25089724-25101501 bp, - strand  Genetic Position: Chr2, 17.06 cM
Alliance: Nelfbtm1.1Roli page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148508
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA frt- and neo-flanked neo cassette was inserted upstream of exon 1, and an additional loxP site was inserted downstream of exon 4. Germ line, flp-mediated recombination removed the neo cassette leaving exons 1 through 4 floxed. (J:148508)
Generation of the Nelfbtm1.1Roli and Nelfbtm1.2Roli alleles
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nelfb Mutation:  24 strains or lines available
References
Original:  J:148508 Amleh A, et al., Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. PLoS One. 2009;4(4):e5034
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory