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RhoTvrm4
Chemically induced Allele Detail
Nomenclature
Symbol: RhoTvrm4
Name: rhodopsin; translational research vision model 4
MGI ID: MGI:3845397
Gene: Rho  Location: Chr6:115931927-115938829 bp, + strand  Genetic Position: Chr6, 53.72 cM
Light-induced degeneration of photoreceptors in RhoTvrm4/Rho+ mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  (129S4/SvJae x C57BL/6J)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Dominant
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rho Mutation:  8 strains or lines available
References
Original:  J:159523 Budzynski E, et al., Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice. J Biol Chem. 2010 May 7;285(19):14521-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/02/2014
MGI 5.19
The Jackson Laboratory