About   Help   FAQ
Htr6tm1Tct
Targeted Allele Detail
Nomenclature
Symbol: Htr6tm1Tct
Name: 5-hydroxytryptamine (serotonin) receptor 6; targeted mutation 1, Laurence H Tercott
MGI ID: MGI:3844587
Gene: Htr6  Location: Chr4:139061108-139075570 bp, - strand  Genetic Position: Chr4, 70.57 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148381
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 300 bp fragment of exon 1 was replaced with a pgk-neo cassette via homologous recombination. Northern blot analysis confirmed the absence of wild-type transcript in brains from homozygous mice. (J:148381)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htr6 Mutation:  12 strains or lines available
References
Original:  J:148381 Bonasera SJ, et al., A null mutation of the serotonin 6 receptor alters acute responses to ethanol. Neuropsychopharmacology. 2006 Aug;31(8):1801-13
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/13/2017
MGI 6.10
The Jackson Laboratory