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Ank1RBC2
Chemically induced Allele Detail
Nomenclature
Symbol: Ank1RBC2
Name: ankyrin 1, erythroid; red blood cell mutant 2
MGI ID: MGI:3844284
Synonyms: Ank-11674
Gene: Ank1  Location: Chr8:22974844-23150497 bp, + strand  Genetic Position: Chr8, 11.42 cM
Mutation
origin
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+ or BALB/c
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU treatment of male mice with Mpltm1Wsa on a BALB/c background induced a G to C transversion located at the splice acceptor site of exon 41. This point mutation induces a frame shift after amino acid 1674 and results in the addition of 96 residues and a premature codon. (J:148127)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ank1 Mutation:  56 strains or lines available
References
Original:  J:148127 Rank G, et al., Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant. Blood. 2009 Apr 2;113(14):3352-62
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2018
MGI 6.12
The Jackson Laboratory