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Nestm1Dopa
Targeted Allele Detail
Nomenclature
Symbol: Nestm1Dopa
Name: nestin; targeted mutation 1, Donghyun Park
MGI ID: MGI:3844224
Gene: Nes  Location: Chr3:87971093-87980451 bp, + strand  Genetic Position: Chr3, 38.78 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148027
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsExon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:168641)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nes Mutation:  3 strains or lines available
References
Original:  J:148027 Park D, et al., The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun. 2009 May 8;382(3):588-92
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory