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Tekt3tm1Zuk
Targeted Allele Detail
Nomenclature
Symbol: Tekt3tm1Zuk
Name: tektin 3; targeted mutation 3, Martin M Matzuk
MGI ID: MGI:3843699
Gene: Tekt3  Location: Chr11:63061654-63094964 bp, + strand  Genetic Position: Chr11, 38.92 cM, cytoband B2
Structural defects in Tekt3tm1Zuk/Tekt3tm1Zuk spermatozoa flagella

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148050
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with an Hprt minigene. The absence of transcript expression was confirmed by northern blot analysis on testes extract. (J:148050)
Generation of the Tekt3tm1Zuk allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tekt3 Mutation:  7 strains or lines available
References
Original:  J:148050 Roy A, et al., Tektin 3 is required for progressive sperm motility in mice. Mol Reprod Dev. 2009 May;76(5):453-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory