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Tg(tetO-Chrnb2*V287L)H3Gica
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Chrnb2*V287L)H3Gica
Name: transgene insertion H3, Giorgio Casari
MGI ID: MGI:3843695
Synonyms: Chrnb2B287L transgene, Tg(TRE-Chrnb2V287L), Tg(TRE-Chrnb2V287L)H3
Transgene: Tg(tetO-Chrnb2*V287L)H3Gica  Location: unknown  Genetic Position: Chr1, Syntenic
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Transgenic mouse lines were derived from three founder animals and designated H1, H3 and H5. Quantitative Southern blot analysis suggests that line H3 carries ~4 tandem copies of the transgene, while lines H1 and H3 each carries a single copy. (J:145855)

References
Original:  J:145855 Manfredi I, et al., Expression of mutant beta2 nicotinic receptors during development is crucial for epileptogenesis. Hum Mol Genet. 2009 Mar 15;18(6):1075-88
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory