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Tg(ACTB-TNFRSF6B)754Jwu
Transgene Detail
Nomenclature
Symbol: Tg(ACTB-TNFRSF6B)754Jwu
Name: transgene insertion 754 Jiangping Wu
MGI ID: MGI:3843671
Synonyms: DcR3 Tg
Transgene: Tg(ACTB-TNFRSF6B)754Jwu  Location: unknown  
Transgene
origin
Strain of Origin:  C3H x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Line 17139 exhibits a phenotype similar to Line 754, including lymphadenopathy, pathologies in skin, kidney and liver and a shortened lifespan in females.

References
Original:  J:148162 Han B, et al., Overexpression of human decoy receptor 3 in mice results in a systemic lupus erythematosus-like syndrome. Arthritis Rheum. 2007 Nov;56(11):3748-58
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory