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Tg(CDX2-cre*)189Erf
Transgene Detail
Nomenclature
Symbol: Tg(CDX2-cre*)189Erf
Name: transgene insertion 189, Eric R Fearon
MGI ID: MGI:3843611
Synonyms: CDX2P9.5-G22Cre
Transgene: Tg(CDX2-cre*)189Erf  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe CDX2P9.5-G22Cre transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a nuclear-localized Cre recombinase gene modified with a 22 guanine nucleotide repeat tract between its initiating methionine (ATG) codon and the remainder of the Cre-coding region, and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic founders (line 189) were found to have approximately 80 copies of the transgene and were bred to C57BL/6J mice. (J:148161)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CDX2     Summary of all recombinase alleles driven by CDX2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:148161 Akyol A, et al., Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nat Methods. 2008 Mar;5(3):231-3
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory