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Esr1tm1.1Awo
Targeted Allele Detail
Nomenclature
Symbol: Esr1tm1.1Awo
Name: estrogen receptor 1 (alpha); targeted mutation 1.1, Andrew Wolfe
MGI ID: MGI:3842661
Gene: Esr1  Location: Chr10:4611593-5005614 bp, + strand  Genetic Position: Chr10, 2.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152925
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The floxed exon 3 and the neo cassette were removed by cre mediated recombination. (J:152925)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esr1 Mutation:  26 strains or lines available
References
Original:  J:152925 Singh SP, et al., Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1). Biol Reprod. 2009 Sep;81(3):488-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory