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Btlatm1Dgra
Targeted Allele Detail
Nomenclature
Symbol: Btlatm1Dgra
Name: B and T lymphocyte associated; targeted mutation 1, Daniel Graf
MGI ID: MGI:3842627
Gene: Btla  Location: Chr16:45224315-45252892 bp, + strand  Genetic Position: Chr16, 29.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147751
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsPart of the promoter and all of exon 1 were removed. Gene inactivation was confirmed by an absence of mRNA detected by Northern blot analysis. (J:147751)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Btla Mutation:  6 strains or lines available
References
Original:  J:147751 Liu X, et al., Cutting edge: A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction. J Immunol. 2009 Apr 15;182(8):4516-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory