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Rag1tm1Jsek
Targeted Allele Detail
Nomenclature
Symbol: Rag1tm1Jsek
Name: recombination activating gene 1; targeted mutation 1, JoAnne Sekiguchi
MGI ID: MGI:3840831
Synonyms: Rag1S723C
Gene: Rag1  Location: Chr2:101638282-101649501 bp, - strand  Genetic Position: Chr2, 53.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146912
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Hypomorph)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rag1 Mutation:  40 strains or lines available
References
Original:  J:146912 Giblin W, et al., Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. Blood. 2009 Mar 26;113(13):2965-75
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory