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Lypd1tm1.1Tmj
Targeted Allele Detail
Summary
Symbol: Lypd1tm1.1Tmj
Name: Ly6/Plaur domain containing 1; targeted mutation 1.1, Thomas M Jessell
MGI ID: MGI:3840549
Synonyms: Lynx2-
Gene: Lypd1  Location: Chr1:125795359-125840838 bp, - strand  Genetic Position: Chr1, 54.7 cM
Alliance: Lypd1tm1.1Tmj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146775
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were removed by germ line, cre mediated recombination. The absence of transcript expression was confirmed by in situ hybridization on brain sections. (J:146775)
Generation of the Lypd1tm1Tmj and Lypd1tm1.1Tmj alleles
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lypd1 Mutation:  13 strains or lines available
References
Original:  J:146775 Tekinay AB, et al., A role for LYNX2 in anxiety-related behavior. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4477-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory