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Kmt2atm1.2Erns
Targeted Allele Detail
Nomenclature
Symbol: Kmt2atm1.2Erns
Name: lysine (K)-specific methyltransferase 2A; targeted mutation 1.2, Patricia Ernst
MGI ID: MGI:3839795
Synonyms: Mll1deltaN
Gene: Kmt2a  Location: Chr9:44803355-44881296 bp, - strand  Genetic Position: Chr9, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147265
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exon 3. This exon codes for several nuclear targeting sequences. (J:147265)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kmt2a Mutation:  79 strains or lines available
References
Original:  J:147265 Jude CD, et al., Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell. 2007 Sep 13;1(3):324-37
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory