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Bcl11btm1.1Leid
Targeted Allele Detail
Nomenclature
Symbol: Bcl11btm1.1Leid
Name: B cell leukemia/lymphoma 11B; targeted mutation 1.1, Mark Leid
MGI ID: MGI:3839576
Synonyms: Bcl11bL2, CTIP2L2
Gene: Bcl11b  Location: Chr12:107910403-108003602 bp, - strand  Genetic Position: Chr12, 59.1 cM, cytoband F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147182
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4 and an frt flanked neo cassette and a second loxP site were inserted downstream of exon 4 via homologous recombination. The frt flanked neo cassette was then removed by Flp mediated recombination. (J:147182)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11b Mutation:  10 strains or lines available
References
Original:  J:147182 Golonzhka O, et al., Dual Role of COUP-TF-Interacting Protein 2 in Epidermal Homeostasis and Permeability Barrier Formation. J Invest Dermatol. 2008 Dec 18;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory