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Targeted Allele Detail
Symbol: Numa1tm1.2Dwc
Name: nuclear mitotic apparatus protein 1; targeted mutation 1.2, Don W Cleveland
MGI ID: MGI:3838103
Synonyms: NuMAdelta22
Gene: Numa1  Location: Chr7:101934111-102014964 bp, + strand  Genetic Position: Chr7, 54.7 cM
Germline Transmission:  Earliest citation of germline transmission: J:146214
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsGerm line, cre mediated recombination was used to remove exon 22. The neo cassette was previously removed by germ line, flp mediated recombination. (J:146214)
Generation of the Numa1tm1Dwc, Numa1tm1.1Dwc, and Numa1tm1.2Dwc alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Numa1 Mutation:  45 strains or lines available
Original:  J:146214 Silk AD, et al., Requirements for NuMA in maintenance and establishment of mammalian spindle poles. J Cell Biol. 2009 Mar 9;184(5):677-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory