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Pard3tm1Shoh
Targeted Allele Detail
Nomenclature
Symbol: Pard3tm1Shoh
Name: par-3 family cell polarity regulator; targeted mutation 1, Shigeo Ohno
MGI ID: MGI:3838016
Synonyms: Par3Neo
Gene: Pard3  Location: Chr8:127063893-127612286 bp, + strand  Genetic Position: Chr8, 74.66 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146415
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 3, and an additional loxP site was inserted downstream of exon 3. (J:146145)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pard3 Mutation:  30 strains or lines available
References
Original:  J:146415 Hirose T, et al., PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development. 2006 Apr;133(7):1389-98
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory