About   Help   FAQ
Gene trapped Allele Detail
Symbol: Trim32Gt(BGA355)Byg
Name: tripartite motif-containing 32; gene trap BGA355, BayGenomics
MGI ID: MGI:3837468
Gene: Trim32  Location: Chr4:65604986-65616238 bp, + strand  Genetic Position: Chr4, 34.43 cM, cytoband C1
Mutant Cell Line:  BGA355
Germline Transmission:  Earliest citation of germline transmission: J:146155
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap
Mutation detailsThe gene trap vector, containing a beta-geo cassette, inserted at nucleotide 410 within exon 2. The absence of transcript expression was confirmed by RT-PCR analysis on brain extracts. Note transcript expression of the flanking gene is normal as confirmed by RT-PCR analysis on brain and skeletal muscle extracts. (J:146155)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trim32 Mutation:  17 strains or lines available
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
Original:  J:146155 Kudryashova E, et al., Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum Mol Genet. 2009 Apr 1;18(7):1353-67
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory