Bdnf^tm1.1Tes
Targeted Allele Detail

Summary

• Symbol: Bdnf^tm1.1Tes
• Name: brain derived neurotrophic factor; targeted mutation 1.1, Lino Tessarollo
• MGI ID: MGI:3836989
• Synonyms: bdnf-HA
• Gene: Bdnf Location: Chr2:109505045-109557352 bp, + strand Genetic Position: Chr2, 56.63 cM
• Alliance: Bdnf^tm1.1Tes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146179
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: Germ line, cre mediated recombination was used to remove the floxed neo cassette and splice acceptor allowing for expression of the HA-tagged allele. (J:146179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bdnf Mutation: 39 strains or lines available

References

• Original: J:146179 Yang J, et al., Neuronal release of proBDNF. Nat Neurosci. 2009 Feb;12(2):113-5
• All: 9 reference(s)