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Trip11Gt(AJ0490)Wtsi
Gene trapped Allele Detail
Summary
Symbol: Trip11Gt(AJ0490)Wtsi
Name: thyroid hormone receptor interactor 11; gene trap AJ0490, Wellcome Trust Sanger Institute
MGI ID: MGI:3836913
Synonyms: GMAP210-
Gene: Trip11  Location: Chr12:101800304-101879463 bp, - strand  Genetic Position: Chr12, 51.3 cM, cytoband F1
Alliance: Trip11Gt(AJ0490)Wtsi page
Omphalocele and cardiovascular and lung defects in Trip11Gt(AJ0490)Wtsi/Trip11Gt(AJ0490)Wtsi mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Mutant Cell Line:  AJ0490
Germline Transmission:  Earliest citation of germline transmission: J:142875
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsThe gene trap vector, which contains a beta-geo cassette, was inserted into intron 4. This allele also contains a 531 bp insertion derived by duplication from chromosome 16 at the junction between the vector and intron 4. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:142875)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trip11 Mutation:  99 strains or lines available
References
Original:  J:142875 Follit JA, et al., The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex. PLoS Genet. 2008 Dec;4(12):e1000315
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory