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Neto1tm1Mci
Targeted Allele Detail
Nomenclature
Symbol: Neto1tm1Mci
Name: neuropilin (NRP) and tolloid (TLL)-like 1; targeted mutation 1, Roderick R McInnes
MGI ID: MGI:3836584
Synonyms: Neto1tlz
Gene: Neto1  Location: Chr18:86413077-86524843 bp, + strand  Genetic Position: Chr18, 58.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145953
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 and 3 were replaced with a tau-lacZ (tlz) and floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:145953)
Generation of the Neto1tm1Mci allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neto1 Mutation:  27 strains or lines available
References
Original:  J:145953 Ng D, et al., Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol. 2009 Feb 24;7(2):e41
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory