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Targeted Allele Detail
Symbol: Neto1tm1Mci
Name: neuropilin (NRP) and tolloid (TLL)-like 1; targeted mutation 1, Roderick R McInnes
MGI ID: MGI:3836584
Synonyms: Neto1tlz
Gene: Neto1  Location: Chr18:86413077-86524843 bp, + strand  Genetic Position: Chr18, 58.47 cM
Germline Transmission:  Earliest citation of germline transmission: J:145953
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 2 and 3 were replaced with a tau-lacZ (tlz) and floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:145953)
Generation of the Neto1tm1Mci allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neto1 Mutation:  27 strains or lines available
Original:  J:145953 Ng D, et al., Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol. 2009 Feb 24;7(2):e41
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory