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Targeted Allele Detail
Symbol: Kdm1atm1.2Tche
Name: lysine (K)-specific demethylase 1A; targeted mutation 1.2, Taiping Chen
MGI ID: MGI:3834630
Synonyms: Aof21lox
Gene: Kdm1a  Location: Chr4:136550540-136602723 bp, - strand  Genetic Position: Chr4, 68.8 cM
Germline Transmission:  Earliest citation of germline transmission: J:144527
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsGerm line, cre mediated recombination was used to remove exons 10 through 13 leading to a frame shift. The absence of protein expression was confirmed by western blot analysis on embryonic stem cells. (J:144527)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm1a Mutation:  30 strains or lines available
Original:  J:144527 Wang J, et al., The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet. 2009 Jan;41(1):125-9
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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