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Kdm1atm1Tche
Targeted Allele Detail
Nomenclature
Symbol: Kdm1atm1Tche
Name: lysine (K)-specific demethylase 1A; targeted mutation 1, Taiping Chen
MGI ID: MGI:3834627
Synonyms: Aof23lox
Gene: Kdm1a  Location: Chr4:136550540-136602723 bp, - strand  Genetic Position: Chr4, 68.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144527
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 10, and a floxed beta-geo cassette was inserted downstream of exon 13. (J:144527)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm1a Mutation:  29 strains or lines available
References
Original:  J:144527 Wang J, et al., The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet. 2009 Jan;41(1):125-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory